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These bioactives, when loaded into nanocarriers like SLNs and NLCs, exhibit enhanced dermal penetration, stability, and controlled release profiles compared to crude extracts, making them more comparable mechanistically to synthetic small-molecule inhibitors

Food Microbiol 79:137146

The label expansion was supported by data from the Phase III ASC4FIRST study, in which 68% of patients treated with Scemblix achieved a major molecular response compared with 49% of those treated with standard-of-care tyrosine kinase inhibitors, including imatinib and nilotinib

Front Neurol 9:455 Gil MJ, Manzano MS, Cuadrado ML, Fernandez C, Gomez E, Matesanz C, Calero M, Rabano A (2018a) Frontotemporal lobar degeneration: Study of a clinicopathological cohort

CKD, chronic kidney disease

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