CD55 Polyclonal Antibody, 100ul[BT-AP02140] Human Genome Knockout Libraries |Contains 1 collagen IV NC1

|Contains 1 collagen IV NC1 (C-terminal non-collagenous) domain

Alternately spliced transcript variants have been observed for this gene

These genes are characterized by several distinct features

and mutations in this gene have been associated with congenital chloride diarrhea

Additional splicing is suggested but complete sequence for further transcripts has not been determined

CD55 Polyclonal Antibody, 100ul[BT-AP02140] Human Genome Knockout Libraries |Contains 1 collagen IV NC1Cortactin, encoded by CTTN gene (formerly EMS1), was originally identified as a substrate of the Src kinase. It is a cytoskeletal protein that interacts with F actin and Arp2 3 complex and plays an important role in regulation of actin assembly and cytoskeleton dynamics. Overexpression of cortactin increases cell migration, and is thought to contribute to the invasive phennotype of breast cancer and several other tumors. Three isoforms of cortactin