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[Article] [PubMed]62

GLP-1 and glucagon both originate from the same parent compound called proglucagon, but they have very different effects

Stentz FB, Lawson D, Tucker S et al

Uncontrolled hypertension - Bupropion may raise blood pressure, especially in patients whose high blood pressure is poorly controlled

This effect was then shown to be mimicked by GLP-1 that acted on the same receptor (94)

These receptor agonists are recognized for their cardioprotective properties and have been approved by the FDA to lower the risk of major adverse cardiovascular events in individuals who are overweight or obese with cardiovascular disease