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Previous studies have indicated that the activation of Akt/GSK3 signaling pathway plays a role in UA-mediated neuroprotection in PD and ALS models [136, 171]

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Diabetes Care 18:779784 Misbin RI, Green L, Stadel BV, Gueriguian JL, Gubbi A, Fleming GA (1998) Lactic acidosis in patients with diabetes treated with metformin