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This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses

Alternative splice variants have been described but their biological validity has not been demonstrated

May function in nuclear protein import as nuclear transport receptor

Mutations in this gene are believed to result in congenital ocular defects

TH Polyclonal Antibody, 20ul[BT-AP08991] High Speed Micro-Centrifuges Efficiently prepare your DNA orTyrosine 3 monooxygenase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.