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Excess adiposity, particularly visceral fat, is associated with reduced GLP-1 secretion and impaired incretin effect

10.3389/fphar.2020.00291 76 LimJ.-O.SongK

There is no approved peptide treatment for IBD or arthritis here

If you want structured support managing your health and body composition alongside medical treatment, working with an online personal trainer who understands the physiology of GLP-1 based therapies can make a real difference in your outcomes.

Some individuals find that they need to titrate up to the maximum dose of a given GLP-1 drug fairly quickly, while others are able to make progress on a lower dose for an extended period

Its use remains confined to clinical trial settings, and any guidance on its management is therefore derived from trial protocols and the broader evidence base for the GLP-1 receptor agonist drug class