MTMR5 Rabbit Polyclonal Antibody, 50ul Cellular Function Assays The corticotropin releasing hormone receptor

The corticotropin releasing hormone receptor 1 is essential for the activation of signal transduction pathways that regulate diverse physiological processes including stress

which represents an unusual regulatory mode for controlling the precise expression of a single gene

The enzyme has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH

and both proteins act together in the regulation of late endocytic traffic

Allelic variants of this gene have been associated with microvascular complications of diabetes 1 (MVCD1) and atherosclerosis

MTMR5 Rabbit Polyclonal Antibody, 50ul Cellular Function Assays The corticotropin releasing hormone receptorThis gene encodes a member of the protein tyrosine phosphatase family. However the encoded protein does not appear to be a catalytically active phosphatase because it lacks several amino acids in the catalytic pocket. This protein contains a Guanine nucleotide exchange factor (GEF) domain which is necessary for its role in growth and differentiation. Mutations in this gene have been associated with Charcot Marie Tooth disease 4B3. Pseudogenes of this