CYTS Polyclonal Antibody, 100ul Molecular Biology ITGAE encodes an I-domain-containing alpha

ITGAE encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain

Alternative splicing yields two isoforms that differ in abundance and expression patterns

The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis

Haploinsufficiency for this protein may contribute to the mental retardation found in haemoglobin H-related mental retardation (ART-16 syndrome)

it is thought that the presenilins are involved in the cleavage of the Notch receptor

CYTS Polyclonal Antibody, 100ul Molecular Biology ITGAE encodes an I-domain-containing alphaThe cystatin superfamily encompasses proteins that contain multiple cystatin like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a