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Intravenous NAC is the standard of care, providing cysteine to regenerate glutathione (Smilkstein et al., N Engl J Med, 1988) [32]

Collectively, our findings reinforce that OCTN2 functions as a highly selective, high affinity transporter, mediating carnitine uptake via a Na + -dependent mechanism that, to our knowledge, has not been observed in the SLC22 family or in MFS transporters more broadly

247 Caloric restriction or its mimetics such as rapamycin can indirectly maintain centromere function by regulating the mTOR pathway

References 1 AgishaV

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This synergy is generally beneficial for cardiovascular outcomes but requires baseline and ongoing monitoring to prevent hypotension