HSF4 Polyclonal Antibody, 20ul Rotator This nuclear protein interacts with

This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs

The encoded protein may play a role in activation of the antiviral prodrug valacyclovir

The myotrophin protein is associated with cardiac hypertrophy

hearing loss

enzyme regulation:Activated by phosphorylation on Ser-52 and Ser-588

HSF4 Polyclonal Antibody, 20ul Rotator This nuclear protein interacts withHeat shock transcription factors (HSFs) activate heat shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.