VE-Cadherin mouse Monoclonal Antibody(8E5), 100ul 3D Culture Aberrant expression of the gene

Aberrant expression of the gene is associated with cancer proliferation in numerous tissues

which have been implicated in childhood lymphoblastic leukemia

This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA)

Alternative splicing of L1CAM results in multiple transcript variants

It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p

VE-Cadherin mouse Monoclonal Antibody(8E5), 100ul 3D Culture Aberrant expression of the geneThis gene encodes a classical cadherin of the cadherin superfamily. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classical cadherin by imparting to cells the ability to adhere in a homophilic manner, this protein plays a