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PLB(Phospho Ser16/T17) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos is essential for heart development

SKU: 28517678237

4.8
SEK111.00 SEK157.00

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PLB(Phospho Ser16/T17) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos is essential for heart developmentThe protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic

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is essential for heart development

Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation

Among its related pathways are Signaling by GPCR and Olfactory Signaling Pathway

They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities

Specific mutations in DYSF have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy

PLB(Phospho Ser16/T17) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos is essential for heart developmentThe protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic

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