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Rapid loss of adiponectin-stimulated fatty acid oxidation in skeletal muscle of rats fed a high fat diet is not due to altered muscle redox state

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& Maini, R

Authors contribution SF: conceptualization, methodology

Inhibition of glutathione metabolism by BSO decreased the ESCC tumor burden To investigate whether glutathione metabolism contributed to the progression of ESCC development, we treated mice bearing ESCC 20 weeks after initial carcinogen treatment with buthionine sulfoximine (BSO), a commonly used chemical inhibitor of -glutamylcysteine synthetase (-GCS) that decreases tissue glutathione concentrations (Figure 3a)

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