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An extended titration does not mean reduced effectiveness

Key takeaways Zepbound and Mounjaro share the same active ingredient, tirzepatide

Additionally, tirzepatide's mechanism of slowing gastric emptying (an effect that is most pronounced initially and tends to diminish with continued treatment) may influence alcohol absorption

Contraception Use of ZEPBOUND may reduce the efficacy of oral hormonal contraceptives due to delayed gastric emptying

doi: 10.1016/S22138587(22)000778 77 DahlDOnishiYNorwoodPHuhRBrayRPatelHet al

Severe, persistent vomiting: If you cannot keep fluids down for more than 24 hours Signs of pancreatitis: Severe abdominal pain radiating to the back, often with vomiting Hypoglycemia symptoms: Shakiness, confusion, sweating, rapid heartbeat