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So while B12 itself is water-soluble and usually flushed out, the context of existing kidney disease changes how the body handles it

Antioxidant therapy represents a promising intervention to mitigate the harmful effects of ROS on reproductive health in additions to its easy accessibility, safety, and low cost

NAC has been used in the treatment of many diseases, including airway cystic fibrosis (Conrad et al., 2015) and nephropathy (Xu et al., 2016)

Since there were too many harms (adverse effects) reported across RCTs, we selected harms that were frequent (1%), as labelled by the Swiss drug compendium, or any serious harms regardless of their frequency.21, 22, 23 Accordingly, we included abdominal pain, constipation, diarrhoea, dizziness, dyspepsia, eructation, fatigue, flatulence, headache, hypoglycemia, injection site reactions, nausea, and vomiting as frequent harms, as well as alopecia, cholecystitis, cholelithiasis, and pancreatitis as moderate to serious harm outcomes

A., Zheng, D., Shibolet, O

These are off-label but some are undergoing research trials