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Beyond the liver, alcohol administration disturbs lipid homeostasis within adipose tissue, triggering a pathological flux of FFA from peripheral fat depots to the liver (Zhong et al., 2012

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For decades, its physiological relevance remained speculative, as the peptide had not yet been identified in human tissue

The L-arginine component in particular has been studied pre-meal, with results showing increased postprandial GLP-1 when taken before eating