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limited clinical data Management: Monitor thyroid function if symptoms of hypothyroidism develop Chemotherapy Agents: Conflicting evidence on interaction with chemotherapy Concern: Taxanes (paclitaxel, docetaxel): Some evidence suggests ALC may worsen CIPN when used during chemotherapy may consider after completion of treatment for established neuropathy Recommendation: Avoid ALC during active chemotherapy

Clayton, MD Professor of Psychiatry and Neurobehavioral Sciences University of Virginia School of Medicine, Charlottesville, Virginia Dr

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