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The harmful conditions that can trigger poliosis include melanoma skin cancer, thyroid disorders, and inflammatory conditions, among others

Aberrant GTPase activity has also been implicated in various pathological conditions [176]

Dimedone is a cell-permeable reagent that exclusively recognizes and binds to cysteines at their sulfenylated form (4E shows representative N-SIM images of T-cells which revealed a slightly increased global dimedone signal in the cytoplasm and on the cell surface upon SFN treatment

Enzymatic examination can be performed by measuring the decreased activity of mitochondrial MCD enzyme in fibroblasts

therefore, age, sex, comorbidities and severity of infection were included in the statistical model to identify differences between groups (Supplementary Table 1)