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or the deficiency of related acyl-CoA (such as propionyl-CoA carboxylase, isobutyryl-CoA dehydrogenase, isovaleryl-CoA dehydrogenase, and succinyl-CoA synthetase) which also have proven to cause the downregulation of free carnitines 11

The dura mater was distended, and no obvious cerebrospinal fluid leakage was observed (Fig

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The final model was subjected to comprehensive validation in MolProbity 37

The following reduction of GSH cell concentration and increase of ROS levels also contributes to cell death 88