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In some cases, GLP-1 medications may not be a good fit

The number of independent biological samples per group is indicated in the figure legends and the Source Data files

Microdosing can sometimes reduce how intense side effects feel, but it does not remove the underlying risks of GLP-1 medications

At its core is Tirzepatide, a next-generation dual agonist that targets both GLP-1 and GIP receptors to help regulate appetite, support metabolic balance, and drive meaningful weight loss

Possible Side Effects and Precautions Common side effects include: Nausea or vomiting (especially in early weeks) Bloating or mild stomach discomfort Fatigue Rare: pancreatitis or gallbladder issues Important: Never start GLP-1 therapy without consulting a doctor