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SR-4 Polyclonal Antibody, 50ul[BT-AP08540] Recombinant Ab Production Chromosomal translocations involving this gene

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SR-4 Polyclonal Antibody, 50ul[BT-AP08540] Recombinant Ab Production Chromosomal translocations involving this geneHTR4 is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5 hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C terminal sequences have been described.

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Description

Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia

The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex

P311 regulates retinoic-acid lipid-droplet biogenesis

Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK)

resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis

SR-4 Polyclonal Antibody, 50ul[BT-AP08540] Recombinant Ab Production Chromosomal translocations involving this geneHTR4 is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5 hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C terminal sequences have been described.

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