DUS14 Polyclonal Antibody, 50ul Recombinant Protein Expression The expression of AIFM2 is

The expression of AIFM2 is also found to be induced by tumor suppressor protein p53 in colon cancer cells

This enzyme is highly expressed in pregnant uterus

Pseudogenes of this gene are located on the long arm of chromosome 13 and the short arm of chromosome 19

Mutations and deletions in this gene are associated with benign hereditary chorea| choreoathetosis| congenital hypothyroidism| and neonatal respiratory distress| and may be associated with thyroid cancer

Mutations in this gene are associated with neutrophil immunodeficiency syndrome

DUS14 Polyclonal Antibody, 50ul Recombinant Protein Expression The expression of AIFM2 isDual specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine based protein tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C terminal catalytic domain but lacks the N terminal CH2 domain found in the MKP