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At baseline, cardiovascular disease and risk factors were managed with lipid-lowering therapy (90%), platelet aggregation inhibitors (86%), angiotensin converting enzyme inhibitors or angiotensin II receptor blockers (74%), and beta blockers (70%)

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Sulfite is then reduced to sulfide by sulfite reductase (SIR) (Takahashi et al., 2011)

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Second, these medications have additional benefits such as weight loss and reduced cardiovascular risk, making them appealing therapeutic options

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N Engl J Med 387(3):205216 Wilding JPH, Batterham RL, Calanna S et al (2021) Once-weekly semaglutide in adults with overweight or obesity

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