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Among 28,953 NAE reports associated with GLP-1 RAs, 19 distinct NAE signals were identified using reporting odds ratios (RORs), including dizziness, tremor, dysgeusia, lethargy, taste disorder, presyncope, parosmia, allodynia, and hypoglycemic unconsciousness, etc

Referral to an endocrinologist is recommended for patients who are pregnant or planning pregnancy, pediatric patients, those with nodules or goiter, discordant laboratory results, persistent symptoms despite normal TSH, or suspected myxedema coma (requiring urgent care)

Patients who underwent cholecystectomy for acute cholecystitis or symptomatic cholelithiasis typically have uncomplicated courses, while those with biliary dyskinesia or postcholecystectomy syndrome may need closer attention

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Additionally, rapid weight loss from injections has been known to cause complications, as mentioned in GLP-1 product liability lawsuits involving DVT, and is an added risk factor for deep vein thrombosis

That distinction is important