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DR10627-family, XGLP/GCG/GIP-32 (Guangxi Medical University / Jiangsu Normal University), TRA24 (Henan University of Technology / Chia Tai Tianqing / Shanghai Duomirui), PB-2309 (PegBio), PN-477 (Protagonist Therapeutics), CS-14 and CS-120070 (Cascade Pharmaceuticals, peptide and small-molecule respectively), FD1016 (Suzhou Yihe), UTG-4 (Guangzhou University of Chinese Medicine), XFL6 (Xi'an Jiaotong First Affiliated Hospital), RAY-0221 (Raynovent, small molecule) - a long tail of Chinese preclinical programs, predominantly peptide-format, mostly targeting obesity with secondary positioning in type 2 diabetes and MASH

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Alzahrani, T.F., Alotaibi, S.M., Alzahrani, A.A., Alzahrani, A.F., Alturki, L.E., Alshammari, M.M., Alharbi, R.A., Alanazi, S.I., Alshammari, W.Z

Role of GLP-1 in Obesity Control GLP-1 has a number of metabolic effects, including glucose-dependent insulin secretion stimulation, decreased stomach emptying, food intake inhibition, increased diuresis, and natriuresis, as well as rodent b-cell proliferation regulation