CD56 Polyclonal Antibody, 50ul[BT-AP01919] Human Genome Knockout Libraries A cryptic ORF at the

A cryptic ORF at the 3' end of this transcript uses a novel internal ribosome entry site and a non-AUG translation initiation codon to produce leucine zipper protein 6

Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms

such as cell division and regulation of insulin sensitivity

Mutations in this gene are associated with nonsyndromic progressive hearing loss

Other transcript variants have been described but their full length nature has not been determined

CD56 Polyclonal Antibody, 50ul[BT-AP01919] Human Genome Knockout Libraries A cryptic ORF at theType IV collagen, the major structural component of basement membranes, is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. COL4A3 encodes alpha 3. In the Goodpasture syndrome, autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli. The