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FAK Monoclonal Antibody, 100ul[BT-MCA0526] 3D Culture PAGE3 is a member of

SKU: 10833657264

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FAK Monoclonal Antibody, 100ul[BT-MCA0526] 3D Culture PAGE3 is a member ofThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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Description

PAGE3 is a member of family of proteins that are expressed in a variety of tumors and in some fetal and reproductive tissues

Tissue-specific utilization of alternative polyA-signal has been described in literature

Studies in rodents suggest that this protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis

The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling

this gene encodes one of the COX assembly factors

FAK Monoclonal Antibody, 100ul[BT-MCA0526] 3D Culture PAGE3 is a member ofThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal

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