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Cortactin(Phospho Tyr466) Polyclonal Antibody, 50ul Yeast Expression In addition to muscle tissues

SKU: 1114285230

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Cortactin(Phospho Tyr466) Polyclonal Antibody, 50ul Yeast Expression In addition to muscle tissuesThis gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase

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Description

In addition to muscle tissues

An important paralog of this gene is COL8A1

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HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system

Interacts with 14-3-3 family members in a phosphorylation-dependent manner

Cortactin(Phospho Tyr466) Polyclonal Antibody, 50ul Yeast Expression In addition to muscle tissuesThis gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase

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