SNPH Polyclonal Antibody, 20ul Antibody Humanization Mutations in this gene are

Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR)

Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits| large and small| that dimerize to form the active enzyme

Alexander disease

and multiple structural subunits encoded by nuclear genes

Fibrinogen-like protein 1 is homologous to the carboxy terminus of the fibrinogen beta- and gamma- subunits which contains the four conserved cysteines of fibrinogens and fibrinogen related proteins

SNPH Polyclonal Antibody, 20ul Antibody Humanization Mutations in this gene areSyntaxin 1, synaptobrevin VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane associated and inhibits SNARE complex formation by binding free syntaxin 1. Expression of this gene appears to be brain specific. Alternative splicing results in multiple transcript variants encoding different isoforms.