NPRL2 Polyclonal Antibody, 100ul Cell Culture Dishes which binds to the promoters

which binds to the promoters of small nuclear and cytoplasmic RNA genes in order to recruit RNA polymerase III

and pancreas (Alanentalo et al

Origin recognition complex subunit 1 contains an OTU domain and binds Ubal (ubiquitin aldehyde)

Oligomerization results from formation of a five-stranded coiled coil and disulfides

The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development

NPRL2 Polyclonal Antibody, 100ul Cell Culture Dishes which binds to the promotersSuppresses Src dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr 9 Tyr 373 and Tyr 376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.