FXL18 Rabbit Polyclonal Antibody, 100ul Organelle Studies similarity:Contains 3 C2H2-type zinc fingers

similarity:Contains 3 C2H2-type zinc fingers

Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP)

Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4)

and thereby plays an important role in axon growth and axon guidance (By similarity)

during an antiviral immune response

FXL18 Rabbit Polyclonal Antibody, 100ul Organelle Studies similarity:Contains 3 C2H2-type zinc fingersThe protein encoded by this gene is a member of a family of proteins that contain an approximately 40 amino acid F box motif. This motif is important for interaction with SKP1 and for targeting some proteins for degradation. The encoded protein has been shown to control the cellular level of FBXL7 a protein that induces mitotic arrest by targeting it for polyubiquitylation and proteasomal degradation. Members of the F box protein family such as FBXL18