PAPD1 Rabbit Polyclonal Antibody, 50ul sgRNA Library Construction Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have been observed

Mutations in this gene cause a multiple congenital anomaly syndrome in human patients

The protein encoded by this gene belongs to the family of potassium channel proteins containing two pore-forming P domains

Transcript variants encoding

Binding of the encoded protein to the SMG1 complex kinase scaffold protein results in the inhibition of its kinase activity

PAPD1 Rabbit Polyclonal Antibody, 50ul sgRNA Library Construction Alternatively spliced transcript variants encodingThe protein encoded by this gene is a member of the DNA polymerase type B like family. This enzyme synthesizes the 3' poly(A) tail of mitochondrial transcripts and plays a role in replication dependent histone mRNA degradation.