SEM6A Polyclonal Antibody, 20ul Cell Culture Dishes and does not allow anions

and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length

The gene encompasses the common fragile site FRA3B on chromosome 3

MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins

May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane

An important paralog of this gene is SERINC2

SEM6A Polyclonal Antibody, 20ul Cell Culture Dishes and does not allow anionsThe transmembrane semaphorin SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection (Leighton et al., 2001