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IRAK-4 Monoclonal Antibody, 50ul Inoculating Loops/Needles Members of the ABC1 subfamily

SKU: 1469285172

4.7
EUR185.00 EUR212.00

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IRAK-4 Monoclonal Antibody, 50ul Inoculating Loops/Needles Members of the ABC1 subfamilyThis gene encodes a kinase that activates NF kappaB in both the Toll like receptor (TLR) and T cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

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Description

Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes

Alternatively spliced transcript variants encoding multiple isoforms have been observed for TCF3

The protein encoded by ACO1 has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions

Polymorphisms in this gene may be associated with type 2 diabetes

RRAD (Ras-Related Associated With Diabetes) is a Protein Coding gene

IRAK-4 Monoclonal Antibody, 50ul Inoculating Loops/Needles Members of the ABC1 subfamilyThis gene encodes a kinase that activates NF kappaB in both the Toll like receptor (TLR) and T cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

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