SNAI2 Rabbit Polyclonal Antibody, 20ul Immunoassays This protein undergoes gamma-secretase dependent

This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined

High levels of expression of SGK1 may contribute to conditions such as hypertension and diabetic nephropathy

This gene has been referred to as USP16 and USP23 but is now known as USP21

Multiple pseudogenes of this gene are located on chromosome 1

Ubiquitin-conjugating enzyme catalyzes the covalent attachment of ubiquitin to other proteins

SNAI2 Rabbit Polyclonal Antibody, 20ul Immunoassays This protein undergoes gamma-secretase dependentThis gene encodes a member of the Snail family of C2H2 type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E box motifs and is also likely to repress E cadherin transcription in breast carcinoma. This protein is involved in epithelial mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.