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Rb Polyclonal Antibody, 100ul[BT-AP07694] Electrophoresis & Labeling test samples

SKU: 15048291471

4.1
EUR123.75 EUR144.75

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Rb Polyclonal Antibody, 100ul[BT-AP07694] Electrophoresis & Labeling test samplesThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

test samples

Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified

subcellular location:Seems to be excluded from nucleoli

These disorders have at least 14 complementation groups

this kit measures IL-1α levels in human samples

Rb Polyclonal Antibody, 100ul[BT-AP07694] Electrophoresis & Labeling test samplesThe protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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