Shc(Phospho Ser36) Polyclonal Antibody, 50ul Cell Proliferation miscellaneous:5 FOXD4-like proteins (FOXD4L2

miscellaneous:5 FOXD4-like proteins (FOXD4L2

Eukaryotic translation initiation factor 2 alpha kinase 3 encoded by EIF2AK3 phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2

Component of the PP4 complexes PPP4C-PPP4R1

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The different subunits arise from alternative splicing in the 3' coding region

Shc(Phospho Ser36) Polyclonal Antibody, 50ul Cell Proliferation miscellaneous:5 FOXD4-like proteins (FOXD4L2This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation.