CT455 Rabbit Polyclonal Antibody, 100ul Enzymes The protein encoded by SDC2

The protein encoded by SDC2 (syndecan 2) is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family

This gene produces two alternatively spliced transcripts

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Alterations of this gene| including point mutations| insertions and deletions| cause factor IX deficiency| which is a recessive X-linked disorder| also called hemophilia B or Christmas disease

It is involved in fibrillar network organization| the anchoring of otoconial membranes and cupulae to the neuroepithelia| and likely in sound stimulation resistance

CT455 Rabbit Polyclonal Antibody, 100ul Enzymes The protein encoded by SDC2This gene represents one of a cluster of several similar genes located on the q arm of chromosome X. The genes in this cluster encode members of the cancer testis (CT) family of antigens and are distinct from other CT antigens. These antigens are thought to be novel therapeutic targets for human cancers. Alternative splicing results in multiple transcript variants.