FLT3(Phospho-Tyr589/591) Rabbit Polyclonal Antibody, 20ul Tubes an inherited peripheral neuropathy

an inherited peripheral neuropathy

The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters

also known as Patau syndrome

Multiple pseudogenes of this gene are found on chromosome 10

is quite deadly and the few who survive past one year suffer from permanent neurologic defects

FLT3(Phospho-Tyr589/591) Rabbit Polyclonal Antibody, 20ul Tubes an inherited peripheral neuropathyThis gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms related tyrosine kinase 3 ligand to the extracellular domain which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis