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PSGL-1 Polyclonal Antibody, 100ul Serum This gene encodes a member

SKU: 1779192561

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PSGL-1 Polyclonal Antibody, 100ul Serum This gene encodes a memberSELPLG encodes a glycoprotein that functions as a high affinity counter receptor for the cell adhesion molecules P , E and L selectin expressed on myeloid cells and stimulated T lymphocytes. As such, selectin P ligand plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post translational modifications, tyrosine sulfation and

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Description

This gene encodes a member of the RING finger protein family of transcription factors

Knockout mice lacking this gene show that it is required for retinal cone bipolar cell differentiation| and that it negatively regulates potassium channel gene expression in the heart to ensure coordinated cardiac repolarization

which phosphorylates multiple target proteins to promote transcriptional elongation

This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis

Diseases associated with C1R include immunodeficiency due to an early component of complement deficiency and c1r/c1s deficiency

PSGL-1 Polyclonal Antibody, 100ul Serum This gene encodes a memberSELPLG encodes a glycoprotein that functions as a high affinity counter receptor for the cell adhesion molecules P , E and L selectin expressed on myeloid cells and stimulated T lymphocytes. As such, selectin P ligand plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post translational modifications, tyrosine sulfation and

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