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PDS5B Polyclonal Antibody, 50ul Lentiviral Packaging The encoded protein is one

SKU: 18151430086

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PDS5B Polyclonal Antibody, 50ul Lentiviral Packaging The encoded protein is oneThis gene encodes a protein that interacts with the conserved protein complex termed cohesin. The cohesin complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor suppressor gene.

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Description

The encoded protein is one of three proteins found in the flavoprotein fraction of the complex

Members of this family are characterized by an N-terminal regulatory domain comprised of a tandem repeat of cysteine-rich zinc-finger motifs and a pleckstrin domain

Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy

Two transcript variants| one protein-coding and the other not| have been found for this gene

and may play an inhibitory role in the control of T-cell proliferation

PDS5B Polyclonal Antibody, 50ul Lentiviral Packaging The encoded protein is oneThis gene encodes a protein that interacts with the conserved protein complex termed cohesin. The cohesin complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor suppressor gene.

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