PRAS40(Phospho-Ser183) Rabbit Polyclonal Antibody, 20ul Monoclonal Antibody Preparation Down-regulation of the encoded protein

Down-regulation of the encoded protein in hepatocellular carcinoma was associated with large tumor size and poor patient survival rates

An important paralog of this gene is POLH

NF-kappa-B inhibitor alpha moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export

K-12 substr

This gene encodes a centrosomal protein required for ciliogenesis and for ciliary tip structural integrity

PRAS40(Phospho-Ser183) Rabbit Polyclonal Antibody, 20ul Monoclonal Antibody Preparation Down-regulation of the encoded proteinAKT1S1 is a proline rich substrate of AKT (MIM 164730) that binds 14 3 3 protein (see YWHAH MIM 113508) when phosphorylated (Kovacina et al. 2003