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Dok-2 Polyclonal Antibody, 100ul[BT-AP02698] Enzyme Activity Assays Has PARP activity and can

SKU: 19715705124

4.1
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Dok-2 Polyclonal Antibody, 100ul[BT-AP02698] Enzyme Activity Assays Has PARP activity and canThe protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

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Description

Has PARP activity and can modify TERF1

ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45

A mutation in this gene results in trismus-pseudocamptodactyly syndrome

This gene belongs to the non-CT (non cancer/testis) subgroup of the melanoma-associated antigen (MAGE) superfamily

and expression of this gene may be a prognostic marker for several types of cancer

Dok-2 Polyclonal Antibody, 100ul[BT-AP02698] Enzyme Activity Assays Has PARP activity and canThe protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

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