RUBIC Rabbit Polyclonal Antibody, 20ul Immunology The protein (BCL2 like 1)

The protein (BCL2 like 1) encoded by BCL2L1belongs to the BCL-2 protein family

and are involved in a variety of biological processes including embryonic development cell growth

• Braking time 2 steps adjustable only for A6-50P rotor

The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal

The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form

RUBIC Rabbit Polyclonal Antibody, 20ul Immunology The protein (BCL2 like 1)The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains an N terminal RUN domain and a C terminal DUF4206 domain. The RUN domain is involved in Ras like GTPase signaling and the DUF4206 domain contains a diacylglycerol (DAG) binding like motif. Mutation in this gene results in deletion of the DAG binding like motif and causes a