Stat4 Polyclonal Antibody, 20ul[BT-AP14543] NGS Oligos another family member

another family member

the encoded protein may contribute to atherosclerosis and aortic valve stenosis in human patients

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This gene is one of a cluster of highly related genes located at chromosomal region 19q13

It is highly expressed in many cancers

Stat4 Polyclonal Antibody, 20ul[BT-AP14543] NGS Oligos another family memberThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.