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C/EBP Epsilon Polyclonal Antibody, 100ul[BT-AP01021] Centrifuges Autoantibodies against this protein are

SKU: 2025969302

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PLN123.75 PLN153.75

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C/EBP Epsilon Polyclonal Antibody, 100ul[BT-AP01021] Centrifuges Autoantibodies against this protein areThe protein encoded by CEBPE is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP delta. The encoded protein (CCAAT enhancer binding protein epsilon) may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare

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Description

Autoantibodies against this protein are found in a subset of patients with dermatomyositis

but is not expressed in differentiated cells

An important paralog of this gene is ANO5

This gene autoregulates its expression by control of splicing of its first two introns

This gene encodes a protein which contains a hinge region domain found in members of the SMC (structural maintenance of chromosomes) protein family

C/EBP Epsilon Polyclonal Antibody, 100ul[BT-AP01021] Centrifuges Autoantibodies against this protein areThe protein encoded by CEBPE is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP delta. The encoded protein (CCAAT enhancer binding protein epsilon) may be essential for terminal differentiation and functional maturation of committed granulocyte progenitor cells. Mutations in this gene have been associated with Specific Granule Deficiency, a rare

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