alpha-E-Catenin(Phospho-Ser652) Rabbit Polyclonal Antibody, 50ul Recombinant Ab Production Mutations in this gene are

Mutations in this gene are associated with Nijmegen breakage syndrome| an autosomal recessive chromosomal instability syndrome characterized by microcephaly| growth retardation| immunodeficiency| and cancer predisposition

This gene encodes a member of a family of solute transporter proteins

High expression seen in the heart and lung

Alternative splicing results in multiple transcript variants encoding distinct protein isoforms

The product of NFATC3

alpha-E-Catenin(Phospho-Ser652) Rabbit Polyclonal Antibody, 50ul Recombinant Ab Production Mutations in this gene areThis gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension resulting in the reconfiguration of cadherin actin filament connections. Certain mutations in