Mouse Caspase 1, CASP1 ELISA Kit, 96T Thermal Control and amidation

and amidation

This protein is chemotactic in vitro for thymocytes and activated T cells| but not for B cells| macrophages| or neutrophils

Among its related pathways are Platelet activation and Ras signaling pathway

Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene

May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K

Mouse Caspase 1, CASP1 ELISA Kit, 96T Thermal Control and amidationThiol protease involved in a variety of inflammatory processes by proteolytically cleaving other proteins, such as the precursors of the inflammatory cytokines interleukin 1 beta (IL1B) and interleukin 18 (IL18) as well as the pyroptosis inducer Gasdermin D (GSDMD), into active mature Peptides (PubMed: 32109412). Plays a key role in cell immunity as an inflammatory response initiator: once activated through formation of an inflammasome complex, it