Rb (Acetyl-K873/K874) Polyclonal Antibody, 50ul Pipette Filler Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to this gene include serine-type endopeptidase inhibitor activity

This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain

This protein can form homodimers or can heterodimerize with another photoreceptor| retinal degeneration slow (RDS)

The P-type adenosinetriphosphatases (P-type ATPases) are a family of proteins which use the free energy of ATP hydrolysis to drive uphill transport of ions across membranes

This gene is the cellular homolog of viral raf gene (v-raf)

Rb (Acetyl-K873/K874) Polyclonal Antibody, 50ul Pipette Filler Gene Ontology (GO) annotations relatedThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.