TRAF2(Phospho-Ser11) Rabbit Polyclonal Antibody, 50ul Reservoirs and a related protein

and a related protein

is a 902 amino acid cytoplasmic protein belonging to the peptidase M14 family

Members of the PDE1 family

The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation

have been implicated in a number of developmental and neurogenetic diseases such as microcephaly

TRAF2(Phospho-Ser11) Rabbit Polyclonal Antibody, 50ul Reservoirs and a related proteinThe protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors and forms a heterodimeric complex with TRAF1. This protein is required for TNF alpha mediated activation of MAPK8 JNK and NF kappaB. The protein complex formed by this protein and TRAF1